Brian and the Eeveelution Family vs. Jaws is an upcoming Family Guy/Pokémon/Universal crossover to be made by Hiatt Grey.
A young woman named Chrissie Watkins leaves an evening beach party on New England's Amity Island to go skinny dipping in the Atlantic Ocean, only to be dragged back and forth and then pulled under the water. Amity's police chief, Martin Brody, is notified that Chrissie is missing, and Deputy Hendricks finds her remains on the beach. The medical examiner informs Brody that she was killed by a shark. Brody plans to close the beaches but is overruled by Mayor Larry Vaughan, who fears that reports of a shark attack will ruin the summer tourist season, the town's primary source of income. The medical examiner consequently attributes the death to a boating accident. Brody reluctantly goes along with the explanation.
A short time later, a boy is killed by a shark at the beach. The boy's mother places a bounty on the shark, sparking an amateur shark-hunting frenzy and attracting the attention of local professional shark hunter Quint. Marine biologist Matt Hooper examines Chrissie's remains and determines that she was unquestionably killed by a shark, not a boat.
A large tiger shark is caught by fishermen, leading the townspeople to believe the problem is solved, but Hooper is unconvinced and asks to examine its stomach contents. Vaughan refuses to make the autopsy public, so Brody and Hooper return after dark and discover the dead shark does not contain human remains. They come across the half-sunken wreckage of a boat belonging to local fisherman Ben Gardner. Hooper explores the vessel underwater and discovers a sizable shark's tooth protruding from the damaged hull before he is startled by Gardner's remains and drops the tooth. Without evidence, Vaughan refuses to close the beaches, and on the Fourth of July many tourists arrive. A children's prank causes panic at the main beach while the shark enters a nearby estuary, killing a man; Brody's son, who witnesses the attack, goes into shock. Brody persuades Vaughan to hire Quint, who reluctantly allows Hooper to join the hunt along with Brody. The three set out to catch and kill the shark aboard Quint's vessel, the Orca.
Brody is given the task of laying a chum line while Quint uses fishing tackle to try to hook the shark. An enormous great white shark looms up behind the boat, and the trio watch it circle the Orca while Hooper takes pictures for research. Quint harpoons it with a line attached to a flotation barrel, but the shark pulls the barrel under and disappears.
The men retire to the boat's cabin, where Quint relates his experience with sharks as a survivor of the sinking of the warship USS Indianapolis during the War in the Pacific in 1945. The shark reappears, damaging the boat's hull before slipping away. In the morning, Brody attempts to call the Coast Guard, but Quint destroys the radio. After a long chase, Quint harpoons another barrel to the shark. The men tie it to the stern, but the shark drags the boat backward, forcing water onto the deck and flooding the engine. Quint heads toward shore, hoping to draw it into shallow waters and suffocate it. In his obsession to kill the shark, Quint overtaxes and stalls the Orca's engines.
With the boat immobilized, the trio attempt a desperate approach: Hooper dons scuba gear and enters the ocean inside a shark proof cage, aiming to stab the shark with a hypodermic spear filled with strychnine. The shark attacks the cage from behind, causing Hooper to drop the spear, When the shark gets tangled in the wrecked cage, Hooper escapes and hides in the seabed,. As Quint and Brody raise the mangled cage, the shark leaps onto the boat, crushing the transom and devouring Quint, who stabs the shark. When the shark attacks, Brody shoves a pressurized scuba tank into its mouth, then takes a rifle and climbs the sinking Orca's mast. Brody shoots at the scuba tank, blowing it and the shark to pieces.
Hooper swims to the surface and laughs about the shark with Brody, and they both use the barrels to swim to shore.
- The Griffin Family, Vinny Griffin, Glenn Quagmire, Cleveland Brown, Joe Swanson, Little Bear, Duck, Cat, Owl, Hen, Emily, Lucy, Doug Funnie, Skeeter Valentine, Belle, Princess Anna, Elsa the Snow Queen, Sunset Shimmer, Human Twilight Sparkle, The Human Mane 5, The Crystal Prep Girls, Blythe Baxter, Zoe Trent, Pepper Clark, Penny Ling, Sunil Nevla, Vinnie Terrio, Minka Mark, Russell Ferguson, Gail Trent, Mitzi, Buttercream Sunday, Sugar Sprinkles, Dudley Puppy, Kitty Katswell, Judy Hopps, Nick Wilde, Natsu Dragneel, Lucy Heartfilia, Erza Scarlet, Gray Fullbuster, Wendy Marvell, Happy, and Carla guest star in this film.
- The storyline continues in Brian and the Eeveelution Family's Adventures of Jaws 2.