Catwoman is a frenenemy of Batman and Pooh and their friends. She is caught in a love-hate relationship with the Caped Crusader and has often crossed paths with Pooh on their adventures. Her real name is Selina Kyle. She is a jewel thief armed with sharp claws on her fingers and a whip. As of the 1990's, she is known as an anti-villainess rather than a traditional villain, since she's considered to be just a common theif, and her alter ego's evoling relationship with Bruce Wayne. In most continuities, she and Bruce know each other's secret identities. She also has a pet cat named Isis. She is one of the Gotham Sirens, along with Poison Ivy and Harley Quinn.
- In episode 53, A Fatal Instinct in Gotham, of Pooh's Adventures Chronicles, Catwoman teams up with Poison Ivy and Harley Quinn in an attempt to take over Gotham City, but just for the money.
- Her portrayers in the live-action films include Michelle Pfieffer in Batman Returns (1992), Halle Berry in her self-titled 2004 bomb, and Anne Hathaway (Jewel) in The Dark Knight Rises (2012), where she's referred to as "The Cat".