Cheerilee is an Earth pony in Ponyville and a supporting character in the show. She teaches at the Ponyville Schoolhouse.
- Cheerilee will meet Winnie the Pooh and his friends in Pooh's Adventures of My Little Pony Friendship is Magic.
- Cheerilee met the FT Squad in The FT Squad's Adventures in My Little Pony: Friendship is Magic.
- Cheerilee is also Miss Frizzle's first best friend.
- Cheerilee is also best friends with Isobella.