This is Donkey's and the heroes bodies got swapped in Crash, Thomas and Ryan meet Shrek the Third.
Crash Bandicoot: Ow. Ryan? You think this is right?
Ryan F-Freeman: [in Thunderblast's voice] Yeah. I hope I can do well.
Shrek: Ryan? What's wrong with your voice?
Sci-Ryan: [in the voice of Kurumi] I think I am ok. That do well with this.
Crash Bandicoot: Sci-Ryan? You got a girl's voice?
[Sci-Ryan in Kurumi's body pops up from a bush]
Kurumi Tokisaki: [in Sci-Ryan's voice] I'm ok. Ryan?
Thunderblast: What? Why are you calling me Ryan? And why is my hands red?