Astronema is the primary antagonist in Power Rangers In Space. She is known throughout the universe as the Princess of Evil, Dark Princess of Space, and the Princess of Darkness. Her name may be a pun off of the Space Constellation, Andromeda.
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- Bowser will eventually create an evil clone of Astronema.
- Astronema (original; Karone) will become Sora, Donald, and Goofy's enemy in Sora's Adventures of Power Rangers in Space, but later their ally after she joins their side when her memory as Karone returned.
- Astronema (original; Karone) will become Storm Hawks' enemy in Storm Hawks' Adventures of Power Rangers in Space, but later their ally after she joins their side when her memory as Karone returned.
- Astronema (original; Karone) will become Max Steel and Team Turbo’s enemy in Max Steel’s Adventures of Power Rangers in Space, but later their ally after she joins their side when her memory as Karone returned.
- Astronema (original; Karone) will become the Galactic Rangers enemy in Ratchet and Clank's Adventures of Power Rangers in Space, but later their ally after she joins their side when her memory as Karone returned.
- Astronema (Karone) will become Ryan Freestar, Meg Griffin, Crash Bandicoot and their friends' enemy in Ryan's Adventures of Power Rangers in Space, but became their ally later after her memory as Karone returned.
- Eventually, in Ryan's Adventures Series, Ryvine will bring Astronema to the present from her time.