Jesse went to Duel Academy as a transfer student, and became quick friends with Jaden. He helped Jaden take down Pr. Viper, who had start survival duels, which were harming the duelists. After Jaden dueled Viper, they were sent to a world by Yubel were Duel Monster spirits were alive. In order to get everyone back home, Jesse stayed behind to finish dueling Yubel, and Jaden was determinded to get him back. Jaden and his friends went back to that world, only to find it completely different than the one they were at. After a long time searching, they found Jesse, but he was possessed by Yubel. Jaden freed him. But Jaden had to defeat Yubel in order to get everyone home. After Jaden combined his sould with Yubel's, Jesse and everyone else were sent back home.
After a long series of adventures, Jaden and his friends reuinte with Jesse, who was his old self from before. Jesse was invited to go on their adventures, and he (along with his Crystal Beast monsters) happily accepted.
- Jesse's main Duel Monster spirit partner is Ruby Carbuncle.
- Jesse is one of the famous Three J's.
- Jesse becomes close friends with Rarity because of their interest in gems.
- Jesse will be Xion's godfather, but not in Toonwriter's projects, because to him, Jesse and Xion are practically around the same age.
- In Jeffrey, Jaden & Friends' Storm Adventures of Star Fox Adventures, Jesse will meet May and fall in love with her.
- Jesse becomes the main protagonist in Jesse, Xion, and Luigi's Mansion.
- Jesse might become a Keyblade wielder.