Elizabeth Brooke McGuire
, famously known as Lizzie, is the main character in the show. She is portrayed as a caring, rational, and cooperative person, although her animated alter-ego displays her true feelings from time to time As the show progresses, she undergoes various image changes, including becoming rebellious, disrespectful and rude in episode Bad Girl McGuire Lizzie constantly gets into arguments with younger broher Matt, but is well-aware of what is right and wrong,


  • She is voiced by Hilary Duff.