Madame Mousey is the primary antagonist of An American Tail: The Mystery of the Night Monster, a pink poodle. She faked being a soothsayer to get money from the mice. She created the Manhattan monster to get rid of the rodents because when she ran away from her owner (the Public Works Chief of New York, a wealthy woman), the other dogs didn't want to be around a dog who looks similar to a rodent, nor did they want any part of her evil schemes. She snapped and got cats to help her make a monster to wipe away all the rodents of New York. She locked them in crates and sold them to cats to be eaten. In the end, Fievel knocks her out by using a live wire to shock her. At the end of the fight with the cats, Tiger and Tony catch Mousey from escaping into the sewer, and the dog council sends her back to her owner. She claimed it was even worse than going to the city pound.