Mukuro's title is Ultimate Soldier (超高校級の「軍人」chō kōkō kyū no “gunjin.”) She has received military training from a very young age and is highly proficient in both a variety of firearms and hand-to-hand combat. When pushed to the limit she can enter a kind of battle trance, where her speed and reflexes increase to nigh-superhuman levels.
Mukuro is the mysterious sixteenth student, and the older twin sister of Junko Enoshima. During the Killing School Life, she disguised herself as her twin sister and was one of the Ultimate Despair members. However, right after the first murder occurred, she was punished by Monokuma (under Junko's control) after breaking the school rules.
Mukuro has a more prominent role in the prequel novel, Danganronpa/Zero, and the alternate ending novel, Danganronpa IF.
Mukuro appeared in Danganronpa 3: The End of Hope's Peak Academy - Side: Despair as one of the Despair Sisters along with Junko.