Continuing where Pooh's Adventures of Stitch! The Movie left off, Lilo and Stitch (along with Winnie the Pooh, Ash Ketchum, Simba, and their friends) are given the task of collecting the rest of Jumba's missing experiments, changing them from bad to good, and finding the one place where they truly belong. Meanwhile, the former Captain Gantu and his reluctant partner, Experiment 625, try to capture the experiments for the imprisoned Dr. Hämsterviel.
- The 100 Acre Wood Rebel Alliance, Ash Ketchum, Pikachu, Misty, Togepi, Brock, The DigiDestined and their Digimon, Simba, Nala, Timon, Pumbaa, Genie, and Louis guest star on this show.
- As of now, the only members of the Jungle Adventure Crew guest starring in this TV series are Simba, Nala, Timon, Pumbaa, Genie, and Louis.