"Pooh's Adventures of Villains Tonight!" tells the tale of Hades as he attempts to hold onto the title of "Lord of the Underworld." After The Fates warn him that he may lose his position as supreme ruler because the Underworld is too happy a place, Hades decides to gather the most powerful Disney villains (Jafar, Maleficent, the Evil Queen, Ursula, Dr. Facilier, Scar, Cruella De Vil, Captain Hook, and Yzma) in an effort to make his underground kingdom a bit more wicked. Accompanied by the likes Pain and Panic from Hercules, his foes Winnie the Pooh, Ash Ketchum, Littlefoot, Simba, Bloom, Ronald McDonald, and their friends, in addition to some of your favorite Disney scoundrels and Winnie the Pooh's arch enemies, Hades sets off on a fun-filled quest brimming with lively musical numbers and wacky antics.
- Ash Ketchum, Pikachu, Misty, Brock, Togepi, Littlefoot, Cera, Ducky, Petrie, Spike, Simba, Nala, Timon, Pumbaa, King Julien, Maurice, Mort, Terk, Tantor, Louis, Genie, Sebastian, King Louie, Fu Dog, Rutt and Tuke, Roger Rabbit, Bloom, Stella, Flora, Musa, Tecna, Layla, Ronald McDonald, Sundea, Birdie, Grimace, Hamburglar, Tika, Franklin, the McNuggets, the Fry Kids, Godzilla and his friends, SpaceGodzilla, and King Ghidorah will guest star in this film.
- RatiganRules originally planned to make this film, but with permission from YakkoWarnerMovies101, he decided to let him make this film instead.
- RatiganRules also originally planned to make a Winx Club crossover with the Disney Cruise Line show, but he decided to let YakkoWarnerMovies101 guest star Bloom and her friends in this film, since RatiganRules is used to Bloom and her friends guest starring in any Pooh's Adventures film.
- A reason why Simba, Nala, Timon, and Pumbaa are in this film is because Scar appeared in the real show.
- A reason why Louis is in this film is because Dr. Facilier once appeared in the real show before he was later removed.
- A reason why Genie is in this film is because Jafar and Iago appeared in the real show.
- A reason why Sebastian is in this film is because Ursula appeared in the real show.