Satan is a recurring villain from South Park, and the main antagonist later antihero of South Park: Bigger Longer & Uncut. However, unlike many portrayals of the ultimate evil, he is portrayed instead as a very flawed antihero and is also openly happy, he is featured heavily in the series as well as the movie and was (in)famous for his relationship with the real-life dictator Saddam. Is the big enemy of God and his son is Antichrist
Ironically Satan is often portrayed as being less malevolent than Saddam but at the same time is the Lord of the Underworld itself (next to Hades) and as such is still an antagonist - though he doesn't really act like it too often.
- Satan will encounter Winnie the Pooh, Ash Ketchum, Simba, SpongeBob SquarePants, and their friends in Winnie the Pooh Goes to South Park: Bigger, Longer & Uncut, in which he will team up with Hades, Pain and Panic, The Flying Dutchman, Sheldon J. Plankton, Scar, Shenzi, Banzai , Ed, The Shredder, Carface, Killer, Belladonna, and Team Rocket (Jessie, James, and Meowth).
- Satan will encounter Littlefoot and his friends in Littlefoot Goes to South Park: Bigger, Longer & Uncut, in which he will team up with Eris, Dr. Facilier, The Horned King, Creeper, Jafar, Maleficent, Myotismon, Ursula, The Machine, The Carnotaurs, The Grand Duke of Owls, Warren T. Rat, Cat R. Waul, Chula, Bowser, Mistress Nine, Bowser Jr., Rothbart, Ozzy and Strut, Ichy and Dil, Rinkus and Sierra, Red Claw, Screech & Thud, Makunga, Stripe, Clayton, Oogie Boogie, and Team Rocket (Cassidy and Butch).
- Satan will make his first guest appearance in a Pokémon crossover film in Ash Ketchum in Fantasmic!.
- Satan will make his first guest appearance in a Land Before Time crossover film in Littlefoot in Fantasmic!.