Smurfette is a female Smurf and the main protagonist in the Smurfs series. She was created by Gargamel to destroy the smurfs by making them want her and protray the other smurfs. Back then, she had a nose just like the other smurfs, and short black hair. She brought into the village when Hefty found her, which explains his strongest love for her. Then because how nice the other smurfs were to her, Papa Smurf put plastic surgery on her which made the smurf she is today, with a smaller nose and long blonde hair. In The Smurfs: A Christmas Carol, she was the Smurf of Christmas Past.
- In the 80's cartoon series, she was voiced by Lucille Bliss, who also did Anastasia Tremaine. In the live-action film series, she is voiced by pop star Katy Perry. In the Sony animated shorts, she is voiced by Melissa Sturm, who also does Ursa. In the upcoming fully animated Smurfs: The Lost Village, she will be voiced by other singer Demi Lovato.
- Smurfette is good friends with Cinderella, Snow White, and Toothiana.
- Smurfette will join Barney's Adventures team in Barney Joins The Smurfs.