Susan Murphy (Ginormica) is human woman who got hit by a meteorite containing Quantonium and became a giantess in Monsters vs. Aliens.
- She was voiced by Reese Witherspoon in the movie, and is being voiced by Riki Lindhome in the TV series.
- One of two of the strongest allies of SpongeBob due to the effects of the alien energy, alongside Thundra, as her sheer size and strength make her a force to be reckoned with.
- She met the Jungle Adventure Crew in Simba, Timon, and Pumbaa's Adventures of Monsters vs. Aliens.
- In Jeffrey & Friends' Adventures of Monsters vs. Aliens, Susan is revealed to be Jeffrey Dragonheart's cousin.
- Susan will meet Ryan and the gang in Crash's, Thomas' and Ryan's Adventures of Monsters Vs. Aliens.