This is how Symbiote bonds with Twilight goes in Ryan's Spider-Man 3 Adventure.
[As Twilight sleeps and haves a nightmare, the symbiote crawls to her bed and briefly turns into a head and growls quietly before turning into a hand going down. Twilight starts having a nightmare about Zeta Prime being killed by Sharpshot. As she has the nightmare, the Symbiote attaches itself to her and starts covering her in black.]
Twilight Sparkle: [in her sleep]
Twilight Sparkle: Where am I?
[Twilight finds herself looking at her reflection in a building glass and her skin has turned black]
Twilight Sparkle: What is this? I feel...wow. This feels good.
[Twilight tests her new flight]
Twilight Sparkle: This is something else.
Twilight Sparkle: What do you think?
Optimus Prime: I've never seen anything like it. I'm a physicist, not a biologist, but...I'll look at it in the morning, run some tests.
Twilight Sparkle: Can we do that now?
[The piece of the Symbiote crawls to Twilight and Twilight puts a cup on it]
Optimus Prime: It seems to like you. Don't let any of that get on you.
Twilight Sparkle: Why not?
Optimus Prime: It has the characteristics of a Symbiote, which needs to bond to a host to survive. And sometimes, these things in nature, when they bind, they can be hard to unbind.