Toothiana (or Tooth) is the mythical tooth collector and the Guardian of Memories in Pooh's Adventures of Rise of the Guardians. Tooth is part human and part hummingbird. Assisted by mini fairies that are split-off extensions of herself, she collects the children's teeth, which hold their most precious memories. Tooth stores them in her palace and returns memories when they are needed the most. It is also seen that Tooth and her mini fairies have a crush on Jack, partially because of his perfectly white teeth that, "sparkle like freshly fallen snow."
- She is voiced by Isla Fisher.
- Tooth will meet Littlefoot and his friends in Littlefoot's Adventures of Rise of the Guardians.
- Tooth will meet Bloom and her friends in Bloom's Adventures of Rise of the Guardians.
- Tooth will meet the Peanuts Gang and their friends in Charlie Brown and Snoopy's Adventures of Rise of the Guardians.
- Tooth's friends with Headless Headmistress Bloodgood.