This is how Twilight's friends lose hope goes in The Return of Thunderwing.
[Rainbow Dash, Pinkie Pie, Rarity, Applejack, Fluttershy, Starlight Glimmer, Trixie, Thorax, and Discord walk through Ponyville with their heads down in defeat, which was transformed into Unicron's image. Thunderwing and Twilight taunt them.]
Thunderwing: Princess traitors!
Twilight Sparkle: Silly foals!
[They ignore them and keep walking]
Thunderwing: Come now you nine, you've got to get into the spirit of things. After all, this is your new home.
[They look at Ponyville]
Rainbow Dash: Not anymore.
[They walk away]
[Thunderwing and Twilight celebrate their victory]